The artist has donated the entirety of his £25k Mercury Prize cash to the MVT, which operates to preserve the UK's small music venues.
Fender was awarded the award on October 16 as his latest record the album was declared the top album of the past year.
Fender has chosen to give the cash to the MVT, in recognition of the crucial part grassroots venues played in his early career.
"I personally would not have achieved what I am doing today if it weren't for all the gigs I played around the area, and further afield, when I was starting out," remarked Fender. "These spaces are iconic, but they are facing challenges."
Beginning in 2023, at least 150 of these venues have permanently closed – approximately one-sixth of the entire UK sector.
Over the past year, top acts such as Pulp, the group Coldplay, Katy Perry and Ed Sheeran have all supported the MVT in its initiatives to support the industry, by applying a modest fee to their ticket costs, which benefits independent venues.
He also took part, collecting more than £100,000 on his recent tour to support thirty-eight local spots across the UK.
The donation helped locations that were dealing with potential shutdown due to difficulties stemming from floods, fire incidents and family tragedies, as well as licensing issues, court cases and noise complaints.
Additional spaces were granted monetary aid in modernizing amenities and technical equipment that helped performers and fans.
"The notion that revenue from concerts in major spaces helps the smaller venues, where it begins for artists like me, is just common sense," Sam Fender has commented.
He is not the first artist to donate his honor winnings to good deeds.
Back when the band won the trophy in 1996 for their album their work, lead singer Cocker stated that the group would donate their prize money to the organization the charity.
That year, musician Ms Dynamite split her prize among multiple organizations, such as the children's charity and a Sickle Cell charity.
"Additionally, I contributed a thousand pounds to the center, to their gymnastics program, because I trained in gymnastics when I was growing up and they required new equipment," the artist told outlets.
Previously, the band gave their funds to the youth organization that nurtured their act, as well as other local music groups.
And winners that year M People donated their winnings to a multiple sclerosis charity after a acquaintance was identified with the illness.
"Receiving the award was sufficient," said artist Heather Small. "The prize was the bonus but we could do without the cherry, because we had the main prize. So our winning impacted the lives of others."
In the past week, the Music Venues Trust announced it had saved a couple of grassroots venues in the South East, by transferring them to local control.
The Joiners in Southampton and The Croft in Bristol were purchased under the Own Our Venues scheme, which is backed by Arts Council England and enthusiasts who buy "shares" in the venues.
